This is a Skeleton I had sculpted in 3D Coat for the purpose of posing and adding to other sculpt scenes and dioramas I'm working on - this is part of a bigger project that I'll post here later. The original sculpt is high poly (millions of polygons), I took this into 3DS Max to try out the retopology modifier and was impressed - I was able to apply the modifier to multiple bones (the entire hands and feet) and retopo them all at once. Edge flow was not a major concern since this will be posed and used for other sculpt projects - but I did rig it quick with CAT for fun, and was able to upload to mixamo, download some animations and re-map them to the CAT rig. Check out the animation clip at the bottom to see the result (the sword is also one of my sculpts, retopologized quickly in max).